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(136) developed an ROS-responsive berberine polymer micelle based on the abnormal elevation of ROS in RA-FLSs, which could increase the uptake of berberine by RA-FLSs, inhibit synovial tissue proliferation, and attenuate the inflammatory response by recognizing ROS and mitochondrial superoxide

Because GHK-Cu relies on signaling rather than chemically exfoliating the skin, it takes time for the collagen cycle to turn over