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This type of study can often lead to subsequent investigations of the function of the candidate biomarker and hence is called hypothesis generating

Research primarily involving animals and individuals with more severe head injury has provided a limited framework for understanding the neuroscience of concussion

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Although stress is also a factor which may influence insulin resistance, no doctor treating individuals with diabetes would consider that those needing higher doses of insulin are mentally unstable, making up their disease, or suffering from the placebo effect