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Although carrier proteins and receptors in relation to vitamin B 6 have not been identified in placenta yet, studies have reported up to 4 times higher plasma PLP concentrations in the newborn compared with those in their mothers (Reference Contractor and Shane47Reference Bjrke-Monsen, Varsi and Sakkestad49) , suggesting the involvement of some unknown active mechanism that transfers vitamin B 6 against its concentration gradient

doi: 10.1186/s13048-018-0457-1 142 ForoozanfardFJamilianMJafariZKhassafAHosseiniAKhorammianHet al

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