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Given the essential role of neurotrophic factors in neuronal plasticity and function, a significant number of psychiatric and neurodegenerative disorders are associated with altered neurotrophic factors levels and expression of their cognate receptors [25, 30, 31]

Weight loss: About 10.8% body-weight reduction at 4.5 mg over 26 weeks in phase 2 [1]

For instance, -hydroxybutyrate (OHB) inhibits histone deacetylases, thereby engaging epigenetic mechanisms and anti-inflammatory pathways, and has been implicated in initiating anti-inflammatory cascades that counteract the pathology of neurological disease