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The aged-rat cohort showed improved Morris water maze performance with the same oral protocol, though with greater variability reflecting the heterogeneous baseline cognitive status of the aged-rat population

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The micro-CT images showed that BLM-induced pulmonary fibrosis was more severe in aged mice compared to the young when they received the same dose, i.e., larger area of regional consolidation, higher HU density, and less air volume in the lung (Fig

Initially investigated for its potential effects on digestive tissue, researchers soon noticed possible activity in other areas of healing biology, including: Connective tissue repair Tendon and ligament healing Muscle recovery Blood vessel formation Inflammatory signaling Gastrointestinal integrity Rather than acting through a single mechanism, researchers believe BPC-157 may interact with multiple pathways involved in tissue repair and regeneration