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Townsend L, Dowds J, OBrien K, Sheill G, Dyer AH, OKelly B, et al

Recent findings show that the abundance of oral pathogens and plaque index are positively correlated with circulating TMAO levels (Hernndez-Ruiz et al., 2024), and elevated TMAO can in turn exacerbate periodontal inflammation and alveolar bone resorption (Wang et al., 2022)

Atherosclerosis represents a state of intense oxidative stress characterized by vascular wall lipid and protein oxidation that contributes to chronic inflammation within the arterial wall, in which CRP is a major player (Figure 7)

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