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BPC-157 has demonstrated broad beneficial effects across preclinical models (tissue injury, inflammatory bowel disease, and central nervous system disorders), giving rise to its reputation as a multi-system repair compound, according to a review published in Pharmaceuticals
doi: 10.7150/ijbs.6996
Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole
The copper content of GHK-Cu formulations has been a theoretical safety consideration, given that excessive copper can be toxic - however, the amounts used in cosmetic and research applications are extremely small, the copper is tightly chelated by the peptide (reducing free copper availability), and topical absorption of copper from these products appears minimal and well below levels that would cause systemic copper accumulation or toxicity
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