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found that in a bleomycin (BLM)-induced PF model, mitochondrial iron deposition in alveolar epithelial type II cells (AECIIs) increase significantly, leading to mitochondrial dysfunction and cellular damage, with the upregulation of the mitochondrial iron transporter Mitoferrin-2 being a key factor (Shao et al., 2024)

Disulfiram, in combination with copper, has emerged as a potent inducer of ferroptosis across various cancer types, including triple-negative breast cancer, renal cell carcinoma, hepatocellular carcinoma, nasopharyngeal cancer, oral squamous cell carcinoma, and non-small cell lung cancer

10.1111/rda.14088 57