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Anti-Inflammatory and Antioxidant Effects GHKCu exhibits potent antiinflammatory activity, lowering key cytokines like TNF and IL6 while suppressing NFB/p38 MAPK signaling in multiple cell and animal models

Modest benefits (1-3% density increases or preventing loss) more realistic

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Screening was performed by the authors with an emphasis on translational relevance to orthopaedic surgery and perioperative decision-making