23 Supplementation of 1 mg daily is recommended for patients with specific risk factors (e.g., bariatric/gastric surgery patients, those with severe malnutrition, chronic alcohol use, chronic hemolytic anemia and conditions with high cell turnover, and use of antimetabolite medications such as methotrexate)
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These may include: Dietary changes: Certain foods and drinks are known to worsen symptoms in some individuals
doi: 10.1016/j.clinbiochem.2012.01.016