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In addition to education on proper treatment administration, the participants of the study also received dietary and physical activity counseling aimed towards achieving 150 minutes of physical activity per week and a 500 calorie deficit per day

The pretreatment with ebselen significantly increased the survived SGN numbers, inhibited the apoptosis, and enhanced the expression of 4-HNE in the cultured SGNs of peroxynitrite + ebselen group compared with the peroxynitrite-only group

A continuous exposure might be necessary for chronic studies, whereas acute investigations might only require a single dose

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