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Intermittent fasting confers protection in CNS autoimmunity by altering the gut microbiota

Both Lactobacillus rhamnosus and Lactobacillus plantarum have the capacity to increase serum vitamin D levels by enhancing the expression of vitamin D receptor in enterocytes of both mice and humans (139)

Moreover, it downregulated oxidative stress-related pro-inflammatory proteins, such as p38 MAPK and NF-B, and decreased the Bax/Bcl-2 ratio, thus reducing apoptosis and enhancing mucosal cell survival

Metabolic flexibilitythe ability to switch efficiently between carbohydrate and fat oxidationis arguably the most important metabolic attribute for ultra-distance performance