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During these early experiments, Pickart observed that plasma from younger individuals appeared to stimulate regenerative processes more effectively than plasma from older adults

One study demonstrated that gluconeogenic intermediates, such as pyruvate, malate, and phosphoenolpyruvate (PEP), are neuroprotective against MPP + toxicity

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The National Institutes of Health Office of Dietary Supplements notes that dietary supplements can interact with medications or medical conditions, reinforcing the importance of discussing supplement use with healthcare professionals