Through a process called S-glutathionylation, glutathione also regulates major DNA repair proteins, such as the Ku70/Ku80 heterodimer used in Non-Homologous End Joining (NHEJ) to repair double-strand breaks
Preclinical models demonstrate that these compounds reduce reactive oxygen species, stabilize mitochondrial membrane potential, enhance mitophagy, and activate NRF2 dependent transcription, which translates into attenuation of ASD like behaviors in VPA, propionic acid, maternal immune activation, and BTBR paradigms (Bambini Junior et al., 2014
Key Ingredients: Purified Water, Glycerine, Caprylic Capric Triglyceride, Isopropyl Myristate, Olivem 1000, Palmitoyl Tripeptide, Coconut oil, Glyceryl Mono Stearate, Ceto Stearryl Alcohol, Sodium PCA, Emulsifying Wax, Niacinamide, Glyceryl Stearate 100, Ethylene Glycol Monostearate, Niacinamide, Sodium Benzoate, Potassium Sorbate, 2-Phenoxyethanol, Titanium Dioxide, Multisal Multilayer, Allantoin, Immid Urea, Xanthan Gum, Hydroxyethyl Urea, Disodium EDTA, Citric Acid, Solanum Lycopersicum extract, Emblica officinalis extract, Calendula officinalis extract, Fragrance
It has been approved for clinical use in the therapy of angina pectoris [210, 211]
