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Upon activation, NLRP3 processes pro-IL-1 and pro-IL-18 into their active forms, triggering a robust inflammatory cascade that recruits immune cells to the wound site

Many patients use it for post-surgery recovery, sports injuries, or chronic joint, tendon, and ligament issues to improve tissue repair and reduce inflammation

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The cells were collected by centrifugation at 2000 g for 5 min and washed in phosphate buffered saline (8 gL 1 NaCl, 0.2 gL 1 KCl, 1.44 gL 1 Na 2 PO 4 , 0.24 g L 1 KH 2 PO 4 , at pH 7.5)