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Description

17-hydroxylase (CYP17A1), the rate-limiting enzyme in androgen biosynthesis, is modulated by PKA and MAPK-dependent phosphorylation

We're talking about effects on tendons, ligaments, muscle, bone, and even the nervous system and gut lining

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Phase I Safety Profile: While topical and low-dose injectable formulations demonstrate high tolerance and minimal systemic toxicity, there is no formal Phase I safety data for chronic 85 mg/day intranasal delivery in humans