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They were getting spondys, they were getting facet syndrome, SI joint syndrome, and they didnt say it specifically, but they referenced a lot of sciatica-type issues, which you would say is kind of more discogenic or herniation-related
Any compound that potentiates this pathway carries a theoretical risk of promoting neoplastic processes (PMID: 34179015) No Chronic Toxicity Data: Long-term effects of sustained HGF/c-Met potentiation are unstudied even in animal models Uncharacterized Dose-Response: The relationship between Dihexa dose and adverse effects in any living system is poorly defined beyond acute preclinical studies No Regulatory Review: Dihexa has never undergone the systematic safety evaluation required for regulatory submission Safety Comparison Summary: Cerebrolysin has a known, well-characterized safety profile from decades of clinical use
Jin L, Kimura S, Zhou Y, Kuroda J, Asou H, Inaba T, Milda T, Konopleva M, Andreeff M , Tabe Y
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