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N Engl J Med 390(11):973983 Siegel RL, Giaquinto AN, Jemal A (2024) Cancer statistics, 2024

During the subacute phase of the pathology, lactate can be utilized as an alternative energy source by some surviving neurons and astrocytes, while concurrently promoting angiogenesis and tissue repair through receptor-mediated signaling (129)

This is particularly useful for longterm hostadapted strains of , such as those persisting in the CF lung, which typically develop a multidrugresistant profile as the result of repeated antibiotic therapies