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Until that process concludes, compounding access remains in a regulatory transition period

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Thus, there has been a big effort in the past decades for creating new experimental methodologies that circumvent the use of animals for toxicological research, without compromising its accuracy

Its history began with a breakthrough by a research team at the University of Texas, USA, in 2017.At that time, NNMT was recognized as a key enzyme in cellular metabolism and energy homeostasis, highly active in adipose tissue and closely linked to obesity, type 2 diabetes, and other metabolic diseases