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Researched effects In a diet-induced-obese mouse study (Neelakantan et al., Biochemical Pharmacology, 2018), subcutaneous 5-Amino-1MQ (20 mg/kg, three times daily, roughly 11 days) produced about 5.1% body-weight loss versus continued weight gain in untreated controls, roughly 35% less epididymal white fat mass, smaller adipocytes, lower plasma cholesterol, and improved glucose tolerance, with no reported change in food intake and no observed adverse effects in the mice

Maquart FX, et al

Aguilera, M., Vergara, P

A 2019 study in Dermatologic Surgery comparing localized versus systemic botulinum toxin for hyperhidrosis found that systemic administration produced more uniform results across larger treatment areas