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The two doses of sCT induced similar numbers of cFos positive neurons in the two genotypes and across all brain areas, suggesting that 3 nmol/kg is sufficient to reach the maximum activation, even in the absence of RAMP 1 and 3

By 48 weeks, the gap widens to 24.2% versus approximately 18-19%

The side effects guide covers what to watch for

The TRIUMPH-1 readout is the one researchers should watch most closely, because it will define the label-level weight-loss claim and because it is the trial that anchors the regulatory submission