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In GHK-Cu, it denotes that the tripeptide glycyl-L-histidyl-L-lysine (GHK) is bound to a copper(II) ion, forming the copper-peptide complex researchers study the Cu specifically distinguishes the copper-bound complex from the standalone GHK peptide, which research has shown behaves differently without the copper ion attached

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Further cause-consequence evidence could be seen in BPC 157-treated rats with high intra-abdominal pressures, as treatment largely abrogated both arterial and venous thrombosis