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H.GordonG.GoldmanJ

reported that paricalcitol modulates the Angiopoietin-2/VEGF/VEGFR2 axis, attenuates TGF- related signaling, and preserves renal tissue architecture in an adriamycin nephropathy model ( In summary, vitamin D exerts renoprotective effects on renal fibrosis by suppressing profibrotic signaling, modulating multiple molecular pathways, and stabilizing the renal microenvironment