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10.1016/j.jtemb.2019.07.005 J

Therefore, deficiency in GPx4 increases the susceptibility to the ferroptotic process, which catalyzes the conversion of polyunsaturated fatty acids into toxic lipid hydroperoxides scaffolded by GPx4

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Scores on the Three-Factor Eating Questionnaire (TFEQ-R18) improved in all treatment groups, with Cagrilintide producing greater improvements than placebo in specific domains: cognitive restraint, notably at 1.2 mg and 4.5 mg, emotional eating notably at 0.3 mg and 2.4 mg, and uncontrolled eating notably at 1.24.5 mg