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DAC vs No-DAC: The Half-Life Divide The Drug Affinity Complex (DAC) is a maleimide-containing moiety that lets the CJC-1295 molecule covalently bind circulating albumin after injection, dramatically extending its half-life to a multi-day range

PGs are synthesized from free arachidonic acid via two isoforms of cyclooxygenase (COX, also referred to as PGH2 synthetase)

doi: 10.1016/j.redox.2023.102922 29 TresguerresFGFTorresJLopez-QuilesJHernandezGVegaJATresguerresIF

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