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Storage conditions (typically 28C, protected from light) and beyond-use dates must follow the sponsor's validated stability data

However, the absorption rate through the gastrointestinal tract is deficient so the physicians at The HCG Institute always recommend giving it via injections

Health experts recommended daily allowances (RDAs) for B12 intake recommendations vary by age, but the recommendations are the same regardless of your sex [1]: - 0 to 6 months 0.4 mcg - 7 to 12 months 0.5 mcg - 1 to 3 years 0.9 mcg - 4 to 8 years 1.2 mcg - 9 to 13 years 1.8 mcg - 14 years and older 2.4 mcg If youre pregnant, the National Institute of Health recommends you ingest at least 2.6 micrograms of B12 per day

In practical terms: using a degraded vial may mean youre administering a lower-effective dose, or in worst case, a contaminated or inactive product