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Published preservative efficacy studies describe a concentration-dependent curve: at 0.9%, bacteriostatic activity suppresses common skin-flora organisms through the documented 28-day multi-dose window

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Techniques such as fluorescence recovery after photobleaching and dynamic contrast-enhanced magnetic resonance imaging (MRI) have demonstrated that interstitial fluid generally moves at a relatively slow velocity, ranging from 0.1 to 10 m/s, depending on the species under consideration [214]