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Neurological Changes : Numbness, tingling, and weakness in hands and feet from nerve damage

Independent replication by groups not affiliated with the original researchers is limited

REDEFINE is an ongoing phase 3 trial acting as market evaluation for both CagriSema and cagrilintide, with 60% randomised to CagriSema, 10% cagrilintide, 10% semaglutide, and 20% placebo, where minimum age at inclusion was 55 years with no upper limit [117]

Works well alongside: Hyaluronic acid Niacinamide Ceramides Gentle moisturizers and lipid-based moisturizers Daily SPF (non-negotiable) Microneedling LED therapy Chemical peels (during the healing phase, not the same day as the peel) Keep separate from: Vitamin C AHAs and BHAs High-strength retinoids The simplest workaround is to alternate