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Damiani, C

Drugs Metabolized by the Mercapturate Pathway or by the Mercapturate/-Lyase Pathway Examples of drug electrophiles (discussed by Silverman, 1992) that are metabolized in part by pathways involving glutathione S -conjugate formation include the anticancer drug busulfan (see the succeeding text), the vasodilator nitroglycerin (Needleman et al., 1969), and the immunosuppressive drug azathioprine (de Miranda et al., 1975)

Proc Natl Acad Sci U S A 101:88412, PMID: 15187230 Into T, Inomata M, Nakashima M, Shibata K, Hcker H, Matsushita K (2008) Regulation of MyD88-dependent signaling events by S nitrosylation retards toll-like receptor signal transduction and initiation of acute-phase immune responses