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Its not that the system is overreacting to exercise its quite the opposite its simply not responding which suggests that the muscle repair and antioxidants and whatever other systems that should be ramping up to ameliorate and heal are on vacation in ME/CFS

In the G protein-mediated pathway, 2-AR binds to G proteins, leading to the activation of downstream effectors such as adenylate cyclase (AC), which increases intracellular cAMP levels and activates cAMP-dependent protein kinase A

I started running a whole lot of these tests on the kids, and after about 6 months of doing it with like 40 or 50 tests coming back, all of a sudden it's like, oh my God, these kids are just completely immune-compromised at the gut level