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doi: 10.1007/s13399-024-05308-8 137

The small hydrophilic molecules include glucuronic acid, glutathione, sulfate, amino acids, and a methyl group, which are catalyzed by glucuronyl transferases, glutathione transferases, sulfotransferases, amino acid transferases, and N- and O-methyltransferases, respectively [21]

A research article about the doseresponse effects of survodutide, a dual agonist of the subcutaneous glucagon receptor and glucagon-like peptide- 1 receptor, on bodyweight loss and HbA1c levels

Although transporter reversal is possible in principle, net glycine release via reverse transport is expected mainly under extreme conditions (e.g., profound depolarization and/or collapse of ionic gradients) and may contribute to maladaptive excitatory cascades rather than constituting a canonical physiological release mechanism (Bridges et al