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The macromolecules of alginate could interact with the macropores and large mesopores (1240 nm), creating a SiNPalginate bioactive nanocomposite coating

It promoted proliferation of B and T cells along with Th1 response in healthy, chronically stressed, ovalbumin antigen immunized and immunocompromised mice (Malik et al., 2007) (Kour et al., 2009) (Sun, 2019)

Of note, creatine has been safely and beneficially administered to patients affected by age-related neurological diseases, including Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, long-term memory deficits, Alzheimer's disease, and stroke (Adhihetty and Beal 2008

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