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In addition, treatment with coumarins isolated from Hydrangea paniculata improved colonic integrity, decreased the Firmicutes-to-Bacteroidetes ratio, reduced the relative abundance of Allobaculum and Desulfovibrio , decreased uremic toxin precursors, and enhanced SCFA production in MN rats [136]

Piperine has been shown to have anti-inflammatory and anti-arthritic properties as well

The marine derived xanthophylls, such as fucoxanthin and astaxanthin, have anti-inflammatory effects and antioxidant activity on different cell lines [56,57]