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doi: 10.1038/nrrheum.2014.137 85 ChoudhuryMYinXSchaefbauerKJKangJHRoyBKottomTJet al

It has also been used to treat premature ejaculation, chronic depression, pancreatitis, Parkinsons disease, and AIDS myelopathy

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[2] The bar for FDA drug approval is extremely high, and many compounds that fall short of that bar still have meaningful clinical utility under medical supervision