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What makes this harder is that your ovary's own antioxidant defences, including glutathione, superoxide dismutase, and catalase, also decline with age, meaning that older eggs face both greater ROS exposure and fewer resources to neutralise it. This creates a cycle of increasing vulnerability, and it's one of the key reasons antioxidant support has attracted so much research attention

Notably, populations with high thyroid antibody status appear to exhibit increased susceptibility to the effects of in-utero exposure to thyroid-disrupting chemicals, emphasizing the potential long-term impact of such exposures on thyroid health ( Interestingly, phytoestrogens, which also act as EDCs, have an influence on thyroid hormones in adolescents as well

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