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REVIEW OF THE LITERATURE Potential therapeutic mechanisms of N-acetylcysteine NAC possesses multiple beneficial pharmacological properties, e.g., anti-inflammatory, antioxidant, minimises cytokine action, modulation release of dopamine, reversing of mitochondrial malfunction, diminishes apoptosis and ferroptosis, improved neurogenesis and boosted glutamate release

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Concurrently, the review places a special emphasis on the clinical validation status of the selected combinations, including at the expense of discussing the most prevalent pharmacokinetic problems, formulation issues, and patient safety concerns