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10.1016/j.yexcr.2018.10.002 84 LaksitoriniM

This protection ensures that a higher concentration of intact glutathione reaches the small intestine, where it can be absorbed into the bloodstream

In fact, it can create DNA strand breaks caused by the formation of NO-dependent reactive species such as peroxynitrite, which directly attack the DNA and cause failure to correct single-strand breaks, leading to the formation of double-strand breaks, which are probably responsible for cell death

FIGURE 11 Molecular docking Ten targets (AKT1, TNF, SRC, EGFR, JUN, VEGFA, CND1, MAPK3, MAPK1, and CREB1) were chosen according to the results of the PPI network as the core targets of FRP for the treatment of AD