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Therefore, oxidative change of this Met into methionine sulfoxide inactivates AAT as a serine protease inhibitor

Interestingly, purified MUC5B + epithelial cells generated organoids that were significantly larger and more numerous than organoids derived from MUC5B cells

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Tetrathiomolybdate, another copper-depleting agent, is under investigation for various breast cancer risk categories: one phase II trial assesses its role in breast cancer with moderate-to-high recurrence risk (NCT00195091), while a phase I/II trial evaluates its effectiveness in reducing relapse risk in high-risk, TNBC (NCT06134375)