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Mice were infected subcutaneously (s.c.) in the skin of both hind feet with 3 10 6 parasites in 50 L of PBS

They found that patients with melanoma whose tumors had high levels of MCT1 had significantly worse overall survival than patients whose melanomas had low levels of the protein

Taken together, these data support the development of a phase I clinical trial of BSO+myeloablative dosing of L-PAM and stem cell support in patients with relapsed and refractory MM

Introduction Amyotrophic Lateral Sclerosis (ALS) is a heterogeneous neurodegenerative disease that primarily affects both upper and lower motor neurons, leading to their progressive degeneration and subsequent, often rapid loss of motor function and death (Brotman et al., 2022)