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This range derives from scaling the effective doses in rat studies (approximately 10 micrograms per kilogram of body weight) to human physiology using established interspecies conversion factors

The full name is des(1-3)IGF-1, meaning the first three N-terminal amino acids (glycine-proline-glutamate) have been cleaved off

(2017) 66:180193.e8

Current single-nucleus RNA-seq datasets from human AD tissue reveal distinct ferroptosis-related transcriptional programs in glial cells, including upregulation of TFRC, FTH1, SLC40A1, and ACSL4, which indicate enhanced iron turnover and lipid peroxidation susceptibility (Leng et al., 2021)