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Mitochondrial dysfunction: a key player in brain aging and diseases

If it is not safe, Ill tell you why

Iwai et al., 2022

This is further exemplified by its HmuY protein, which can efficiently sequester heme from Bacteroides fragilis proteins like BfrA, potentially disrupting microbial mutualism in the gut and exacerbating dysbiosis ( P.g exhibits a pronounced tropism for the intestinal mucosa, demonstrating a higher adhesive capacity to intestinal epithelial cells compared to other oral bacteria like Prevotella intermedia , an action primarily mediated by its gingipain proteases (Motosugi et al., 2025)