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For example, SLC38A5 has been implicated in gemcitabine resistance by reducing lipid ROS through the regulation of GSH levels and the mTOR-SREBP1 signaling pathway

The SLC46A1 gene is located on chromosome 17q11.2 and is composed of 6 exons that generate two alternatively spliced mRNAs with the major apical membrane-localized protein being the larger isoform 1 (459 amino acids)

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