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After entering the circulatory system, SCFAs could be distributed in many peripheral tissues, such as the heart, kidney, skin, and sympathetic ganglia (8386), and modulate biological processes through binding to G-protein coupled receptors (GPR41, GPR43, and GPR109A) or inhibiting histone acetylation (87)

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Close examination of the B act complexes (PDB: 8I0R 16 and PDB: 5Z57 13 ) identified a contact point between SF3B1 and SNIP1 and non-interpreted density in the loops of the FHA domain of SNIP1 (Fig