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Transduced quizartinib-resistant MOLM-14 cells 80 were selected in puromycin for 57 days and cultured for an additional 10 days before assessing overexpression of MTA1 by western blotting and panobinostat sensitivity

DNA damage, discoordinated gene expression and cellular senescence in osteoarthritic chondrocytes

Borrell-Pags M, Canals JM, Cordelires FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, et al

Establishing unified and standardized OA animal models, local administration protocols, and comprehensive efficacy evaluation systems will be key to promoting the translation of ferroptosis-targeted therapies from the laboratory to the clinic