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The opioid growth factor connection: LDN and endogenous peptides Low-dose naltrexone (LDN) is not a peptide itself, but its mechanism of action revolves entirely around endogenous peptide systems

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What a COA Should Include Identity confirmation Mass spectrometry confirming the correct molecular weight (~504 Da for Dihexa) Confirmation that the tested compound matches CAS 1401708-83-5 / PNB-0408 Purity testing HPLC purity reputable listings claim ~98% or higher An HPLC chromatogram showing a single dominant peak, not a cluster of unresolved peaks Contamination testing Residual solvent analysis (especially relevant given DMSO-based transdermal forms) Heavy metals screening where the supplier provides it How to Verify a COA Is Legitimate Match the batch