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These enzymes increase the effectiveness of GSH, and patients with mutations in GST can be at greater risk of suffering from environmental toxins

References Qaseem A, Dallas P, Forciea MA, Starkey M, Denberg TD (2014) Dietary and pharmacologic management to prevent recurrent nephrolithiasis in adults: a clinical practice guideline from the American College of Physicians

Similar therapeutic effects were also observed on Huh7 xenografts, where BAY-876SU056 combination treatment dramatically dampened tumor growth (Extended Data Fig

Injectable forms remain the benchmark for consistent systemic exposure, though local or compartmental activity may be feasible for some molecules designed for oral stability