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Outro aspecto que despertou interesse dos pesquisadores foi a capacidade da molcula de influenciar a atividade de milhares de genes humanos relacionados ao crescimento nervoso, resposta antioxidante, ao reparo celular e inflamao

NK cells promote neutrophil recruitment in the brain during sepsis-induced neuroinflammation

These data are first evidence that cereulide high producers rapidly oligomerize the precursor depsipeptides followed by subsequent cyclization, whereas less productive strains seem to accumulate NRPS-bound intermediates at the stage of tetradepsipeptides, only slowly converting them to higher oligomers

References Picardi A, Gigantesco A, Tarolla E, Stoppioni V, Cerbo R, Cremonte M, et al