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GLUTATHIONE REDOX CYCLE Hydrogen peroxide is rapidly reduced to water mostly by Gpx, which utilizes the reducing equivalents from its substrate GSH

In a recent randomized, double-blind, placebo-controlled trial in 70 women with PMS, the daily supplementation with 0.2 g of curcumin for 10 days during three consecutive menstrual cycles significantly reduced overall PMS severity, as assessed by a composite measure of all emotional, behavioral, and physical symptoms (105)

AOD-9604s lack of IGF-1 impact may make it more appropriate for individuals with these concerns, though individual medical evaluation remains essential

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