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The compound was developed by Peter de Keizer and colleagues at Erasmus University Medical Center (Rotterdam) and published in a landmark 2017 Cell paper (Baar et al., Cell 169:132-147) demonstrating selective induction of apoptosis in cellular senescence research models

Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis

In controlled rodent studies [4] evaluating bone and muscle parameters, selective GHS administration preserved bone formation indices and muscle functional output without systemic endocrine disruption