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A decline in the bodys antioxidant defenses may be linked to an increased risk of complications associated with DM [311,312,313]

However, in the non-senescent control fibroblast model cultured in 10% FBS DMEM treated with or without FOXO4-DRI (25 M), no SA--gal-positive cells were observed both in keloid fibroblasts and in normal skin fibroblasts (Supplementary Fig

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